A growing body of peer-reviewed studies is showing the efficacy of Hyperbaric Oxygen Therapy (HBOT) in the treatment of persistent post-concussion symptoms (PPCS) and traumatic brain injury (TBI). You can contact our office to find out more about this TBI treatment option.
Peer-Reviewed References to Support the Use of HBOT for Concussion and TBI Rehabilitation
Clinical efficacy of hyperbaric oxygen combined with different timings of right median‐nerve electrical stimulation in patients with brain injury‐induced disorders of consciousness
Liu YS, Liu ZB, Yang Z, Zhao L, Li HL.
Brain Behavior. 2022 Sep;12(9):e2716. Epub: 2022 Aug 3.
The effect of hyperbaric oxygen therapy on cognition, performance, proteomics, and telomere length—The difference between zero and one: A case report
Maroon, Joseph C.
Frontiers Neurology. 29 July 2022 (Vol 130′ Sec. Experimental Therapeutics
Systematic Review and Dosage Analysis: Hyperbaric Oxygen Therapy Efficacy in Mild Traumatic Brain Injury Persistent Postconcussion Syndrome
Harch, Paul G.
Frontiers Neurology. 17 March 2022 (vol. 13): Sec. Neurotrauma
The National Brain Injury, Rescue and Rehabilitation Study – a multicenter observational study of hyperbaric oxygen for mild traumatic brain injury with post-concussive symptoms.
Mozayeni BR, Duncan W, Zant E, Love TL, Beckman RL, Stoller KP
Medical Gas Research. 2019;9(1):1-12
Hyperbaric oxygen therapy can induce angiogenesis and regeneration of nerve fibers in traumatic brain injury patients.
Tal, Sigal, et al.
Frontiers in Human Neuroscience. 2017; 11: 508
Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury.
Tal, Sigal, et al.
Restorative Neurology and Neuroscience. 33.6 (2015): 943-951
The Effect of Hyperbaric Oxygen on Persistent Post-concussion Symptoms.
Cifu DX, Hart BB, West SL, Walker W, Carne W
The Journal of Head Trauma Rehabilitation. 2014 Jan-Feb;29(1):11-20
Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury – Randomized Prospective Trial
Rahav Boussi-Gross ,Haim Golan ,Gregori Fishlev,Yair Bechor,Olga Volkov,Jacob Bergan, Mony Friedman, Dan Hoofien, Nathan Shlamkovitch, Eshel Ben-Jacob , Shai Efrati;
PLOS ONE. November 15, 2013
The effect of hyperbaric oxygen on symptoms after mild traumatic brain injury.
Wolf G, Cifu D, Baugh L, Carne W, Profenna L
Journal of Neurotrauma. 2012 Nov 20;29(17):2606-12
A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and post-traumatic stress disorder.
Harch, PG, Andrews SR, Fogarty EF, et al.
Journal of Neurotrauma. 2012 Jan 1;29(1):168-85
Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports.
Stoller, KP
Medical Gas Research. 2011, 1:17
Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report
Harch, PG, Fogarty, EF, Staab, PF, et al.
Cases Journal. 2009, 2:6538
Oxygen-induced mitochondrial biogenesis in the rat hippocampus.
Gutsaeva, DR, Suliman, HB, Carraway, MS
Neuroscience. Volume 137, Issue 2, 2006, Pages 493–504
Improvement in cerebral metabolism in chronic brain injury after hyperbaric oxygen therapy.
Golden ZL, Neubauer R, Golden CJ, Greene L, Marsh J, et al.
The International Journal of Neuroscience. 2002 Feb;112(2):119-31
The results of a prospective, randomized trial for treatment of severely brain-injured patients with hyperbaric oxygen.
Rockswold GL, Ford SE, Anderson DC, et al.
Journal of Neurosurgery. 76:929-934, 1992
Hyperbaric-oxygen treatment of multiple sclerosis: a randomized placebo-controlled, double-blind study
Fischer BH, Marks M, Reich T.
New England Journal of Medicine. 1983;308:181-186
